| Mexico U23 League | 04/27 15:30 | 17 | Pachuca U23 v Mazatlan FC U23 | L | 5-1 | |
| Mexico U23 League | 04/19 16:00 | 16 | [16] Mazatlan FC U23 v Juarez FC U23 [7] | L | 0-1 | |
| Mexico U23 League | 04/12 15:00 | 15 | [14] Queretaro U23 v Mazatlan FC U23 [15] | L | 2-1 | |
| Mexico U23 League | 04/05 16:00 | 14 | [13] Mazatlan FC U23 v Unam Pumas U23 [4] | L | 0-3 | |
| Mexico U23 League | 03/29 16:00 | 13 | [13] Mazatlan FC U23 v Tijuana U23 [18] | D | 1-1 | |
| Mexico U23 League | 03/16 15:00 | 12 | Tigres UANL U23 v Mazatlan FC U23 | W | 0-2 | |
| Mexico U23 League | 03/10 15:00 | 11 | Monterrey U23 v Mazatlan FC U23 | L | 4-3 | |
| Mexico U23 League | 03/01 16:00 | 10 | [15] Mazatlan FC U23 v Necaxa U23 [2] | W | 2-1 | |
| Mexico U23 League | 02/25 17:00 | 8 | [12] Santos Laguna U23 v Mazatlan FC U23 [15] | L | 3-0 | |
| Mexico U23 League | 02/21 15:00 | 9 | [17] Club America U23 v Mazatlan FC U23 [15] | D | 2-2 | |
| Mexico U23 League | 02/16 16:00 | 7 | [17] Mazatlan FC U23 v Chivas Guadalajara U23 [16] | W | 3-0 | |
| Mexico U23 League | 02/09 16:00 | 6 | [18] Mazatlan FC U23 v Atlas U23 [15] | D | 1-1 | |
| Mexico U23 League | 02/02 15:00 | 5 | [13] Puebla U23 v Mazatlan FC U23 [16] | L | 3-2 | |
| Mexico U23 League | 01/30 16:00 | 4 | [18] Mazatlan FC U23 v Leon U23 [13] | W | 1-0 | |
| Mexico U23 League | 01/27 15:00 | 3 | [13] Cruz Azul U23 v Mazatlan FC U23 [17] | L | 3-0 | |
| Mexico U23 League | 01/20 15:00 | 2 | [4] Toluca U23 v Mazatlan FC U23 [15] | L | 2-0 | |
| Mexico U23 League | 01/12 16:00 | 1 | [2] Mazatlan FC U23 v Atletico San Luis U23 [2] | L | 0-1 | |
| Mexico U23 League | 11/10 16:00 | 17 | [9] Mazatlan FC U23 v Toluca U23 [15] | L | 0-1 | |
| Mexico U23 League | 11/05 15:00 | 16 | [5] Necaxa U23 v Mazatlan FC U23 [7] | D | 1-1 | |
| Mexico U23 League | 11/01 16:00 | 15 | [9] Mazatlan FC U23 v Santos Laguna U23 [7] | W | 2-1 | |
| Mexico U23 League | 10/27 16:00 | 14 | [11] Mazatlan FC U23 v Queretaro U23 [16] | W | 2-1 | |
| Mexico U23 League | 10/20 15:00 | 13 | [5] Atlas U23 v Mazatlan FC U23 [10] | L | 1-0 | |
| Mexico U23 League | 10/06 16:00 | 12 | [8] Mazatlan FC U23 v Club America U23 [10] | L | 1-2 | |
| Mexico U23 League | 09/30 16:00 | 10 | [10] Mazatlan FC U23 v Tigres UANL U23 [2] | W | 4-0 | |
| Mexico U23 League | 09/26 15:00 | 11 | Chivas Guadalajara U23 v Mazatlan FC U23 | D | 2-2 | |
| Mexico U23 League | 09/22 15:00 | 9 | [16] Atletico San Luis U23 v Mazatlan FC U23 [11] | W | 1-2 | |
| Mexico U23 League | 09/15 16:00 | 8 | [9] Mazatlan FC U23 v Cruz Azul U23 [18] | D | 1-1 | |
| Mexico U23 League | 09/09 16:00 | 5 | [15] Mazatlan FC U23 v Puebla U23 [4] | W | 3-0 | |
| Mexico U23 League | 09/02 15:00 | 7 | [10] Juarez FC U23 v Mazatlan FC U23 [17] | D | 2-2 | |
| Mexico U23 League | 08/25 23:45 | 6 | [16] Tijuana U23 v Mazatlan FC U23 [14] | L | 2-0 |