| Mexico U23 League | 05/13 00:00 | 2 | [2] Atletico San Luis U23 v Pachuca U23 [3] | L | 0-3 | |
| Mexico U23 League | 05/09 15:30 | 2 | [3] Pachuca U23 v Atletico San Luis U23 [2] | L | 1-0 | |
| Mexico U23 League | 05/06 00:00 | 3 | [2] Atletico San Luis U23 v Leon U23 [7] | D | 1-1 | |
| Mexico U23 League | 05/02 15:00 | 3 | Leon U23 v Atletico San Luis U23 | D | 2-2 | |
| Mexico U23 League | 04/28 17:30 | 17 | [13] Santos Laguna U23 v Atletico San Luis U23 [3] | W | 0-3 | |
| Mexico U23 League | 04/19 15:00 | 16 | [3] Atletico San Luis U23 v Toluca U23 [14] | W | 1-0 | |
| Mexico U23 League | 04/14 15:00 | 15 | [12] Atlas U23 v Atletico San Luis U23 [3] | D | 0-0 | |
| Mexico U23 League | 04/07 15:00 | 14 | [6] Atletico San Luis U23 v Juarez FC U23 [4] | W | 5-0 | |
| Mexico U23 League | 03/29 15:00 | 13 | [17] Club America U23 v Atletico San Luis U23 [7] | W | 0-1 | |
| Mexico U23 League | 03/17 15:00 | 12 | [10] Atletico San Luis U23 v Pachuca U23 [8] | W | 3-2 | |
| Mexico U23 League | 03/08 15:00 | 11 | [2] Necaxa U23 v Atletico San Luis U23 [4] | L | 4-1 | |
| Mexico U23 League | 03/01 15:00 | 10 | [5] Atletico San Luis U23 v Puebla U23 [7] | D | 1-1 | |
| Mexico U23 League | 02/27 15:00 | 9 | [17] Queretaro U23 v Atletico San Luis U23 [9] | W | 1-2 | |
| Mexico U23 League | 02/24 15:00 | 8 | Leon U23 v Atletico San Luis U23 | W | 2-3 | |
| Mexico U23 League | 02/17 15:00 | 7 | [15] Atletico San Luis U23 v Tijuana U23 [11] | W | 1-0 | |
| Mexico U23 League | 02/10 15:00 | 6 | [5] Cruz Azul U23 v Atletico San Luis U23 [13] | L | 1-0 | |
| Mexico U23 League | 02/04 15:00 | 5 | [12] Atletico San Luis U23 v Chivas Guadalajara U23 [14] | D | 1-1 | |
| Mexico U23 League | 01/27 15:00 | 3 | [3] Monterrey U23 v Atletico San Luis U23 [6] | D | 2-2 | |
| Mexico U23 League | 01/24 15:00 | 4 | Atletico San Luis U23 v Tigres UANL U23 | L | 0-1 | |
| Mexico U23 League | 01/19 15:00 | 2 | Atletico San Luis U23 v Unam Pumas U23 | D | 2-2 | |
| Mexico U23 League | 01/12 16:00 | 1 | [2] Mazatlan FC U23 v Atletico San Luis U23 [2] | W | 0-1 | |
| Mexico U23 League | 11/11 15:00 | 17 | [18] Atletico San Luis U23 v Santos Laguna U23 [8] | D | 2-2 | |
| Mexico U23 League | 11/04 15:00 | 16 | [2] Tigres UANL U23 v Atletico San Luis U23 [18] | L | 4-0 | |
| Mexico U23 League | 11/01 15:00 | 15 | Atletico San Luis U23 v Club America U23 | L | 1-3 | |
| Mexico U23 League | 10/29 15:00 | 14 | [15] Toluca U23 v Atletico San Luis U23 [18] | D | 2-2 | |
| Mexico U23 League | 10/25 15:00 | 11 | [10] Juarez FC U23 v Atletico San Luis U23 [18] | L | 1-0 | |
| Mexico U23 League | 10/22 15:00 | 13 | [18] Atletico San Luis U23 v Necaxa U23 [6] | L | 0-1 | |
| Mexico U23 League | 10/08 16:00 | 12 | Tijuana U23 v Atletico San Luis U23 | L | 2-1 | |
| Mexico U23 League | 09/29 15:00 | 10 | Atletico San Luis U23 v Cruz Azul U23 | L | 1-3 | |
| Mexico U23 League | 09/22 15:00 | 9 | [16] Atletico San Luis U23 v Mazatlan FC U23 [11] | L | 1-2 |